{"created":"2023-05-15T11:00:36.135980+00:00","id":18,"links":{},"metadata":{"_buckets":{"deposit":"ce3d3cf1-60a1-49f2-9e83-3f18bd788ecc"},"_deposit":{"created_by":3,"id":"18","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18"},"status":"published"},"_oai":{"id":"oai:kio.repo.nii.ac.jp:00000018","sets":["15","15:16"]},"author_link":["32","33"],"control_number":"18","item_10002_biblio_info_7":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"8","bibliographicPageStart":"1","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"畿央大学紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of Kio University","bibliographic_titleLang":"en"}]}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"ゲノム編集とは、動物や植物、培養細胞において、ゲノム上の標的遺伝子の破壊や一塩基置換、レポーター遺伝子のノックインなどを可能にする遺伝子改変技術である。核酸を切断する酵素（ヌクレアーゼ） により二本鎖DNAを切断し、それに続く修復反応によって遺伝子改変を行う。広範囲にわたる生物種に利 用でき、これまでの遺伝子組換えによるモデル生物・モデル細胞の作製に比べて簡易で効率よく遺伝子の改 変ができるため、生命科学の基礎研究、医学研究、産業への利用と様々な分野で急速に広まっている。本稿 ではゲノム編集の基本的な原理、研究・医療・産業での利用、利用に際しての倫理的な問題について解説する。","subitem_description_type":"Other"}]},"item_10002_identifier_registration":{"attribute_name":"identifier_registration","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24482/00000009","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"畿央大学","subitem_publisher_language":"ja"}]},"item_10002_source_id_11":{"attribute_name":"item_10002_source_id_11","attribute_value_mlt":[{"subitem_source_identifier":"AA11989647","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"item_10002_source_id_9","attribute_value_mlt":[{"subitem_source_identifier":"1349-5534","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"前原, 佳代子","creatorNameLang":"ja"},{"creatorName":"マエハラ　カヨコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"32","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kayoko, MAEHARA","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"33","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-06-13"}],"displaytype":"detail","filename":"KK.1401.01-08.pdf","filesize":[{"value":"972.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"KK.1401.01-08.pdf","url":"https://kio.repo.nii.ac.jp/record/18/files/KK.1401.01-08.pdf"},"version_id":"3cb32215-74a3-4599-b86b-610bcfa0ad86"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ゲノム編集","subitem_subject_scheme":"Other"},{"subitem_subject":"ZFN","subitem_subject_scheme":"Other"},{"subitem_subject":"TALEN","subitem_subject_scheme":"Other"},{"subitem_subject":"CRISPR-Cas","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"未来を変えるゲノム編集","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"未来を変えるゲノム編集","subitem_title_language":"ja"},{"subitem_title":"A versatile technology for targeted genome editing has an impact on our lives.","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"3","path":["15","16"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-06-12"},"publish_date":"2017-06-12","publish_status":"0","recid":"18","relation_version_is_last":true,"title":["未来を変えるゲノム編集"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-10-03T09:50:26.120220+00:00"}